i would suggest disabling flipper. the library is not the most reliable and in the best case it will double your build times. if you were using it for debugging, consider this instead https://twitter.com/notbrent/status/1575236873290919936
here is a long thread discussing this error: openssl/opensslv.h' file not found · Issue #28409 · facebook/react-native · GitHub
and a discussion on stackoverflow: reactjs - React Native - npx react-native run-ios doesn't work after initializing the project - Stack Overflow